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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPRD1A
All Species:
25.76
Human Site:
S109
Identified Species:
43.59
UniProt:
Q96P16
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.08
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q96P16
NP_060640.2
312
35720
S109
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Chimpanzee
Pan troglodytes
XP_001136630
316
36166
S109
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Rhesus Macaque
Macaca mulatta
XP_001105423
312
35728
S109
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Dog
Lupus familis
XP_866582
318
36360
S115
L
S
I
W
E
E
R
S
V
Y
E
N
D
V
L
Cat
Felis silvestris
Mouse
Mus musculus
Q8VDS4
312
35682
S109
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Rat
Rattus norvegicus
XP_001056597
417
46600
S214
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001512622
400
45577
S197
K
H
L
G
R
V
L
S
I
W
E
E
R
S
V
Chicken
Gallus gallus
Q5ZM30
268
30818
P75
Q
N
S
K
R
K
G
P
E
F
T
K
D
F
A
Frog
Xenopus laevis
NP_001088920
325
36694
I122
G
V
Y
T
S
D
F
I
Q
Q
L
R
L
A
I
Zebra Danio
Brachydanio rerio
NP_955850
335
38090
S132
L
K
L
T
I
D
D
S
E
S
P
K
H
K
T
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
XP_396379
332
37569
T129
A
E
F
K
A
A
F
T
D
T
S
R
D
P
G
Nematode Worm
Caenorhab. elegans
P34281
315
36355
K114
G
K
L
I
N
V
W
K
D
R
Q
I
F
T
P
Sea Urchin
Strong. purpuratus
XP_779930
352
40189
A148
I
A
E
P
E
D
E
A
V
S
P
P
Q
Q
D
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Q05543
409
46470
N111
K
K
L
S
R
V
V
N
I
L
K
E
R
N
I
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.7
99.6
98.1
N.A.
98.7
73.8
N.A.
71.2
78.2
64
60.9
N.A.
N.A.
49
24.1
46
Protein Similarity:
100
98.7
100
98.1
N.A.
99.3
74.3
N.A.
74.7
83.3
80.3
78.2
N.A.
N.A.
66.8
47.2
63.9
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
100
6.6
0
13.3
N.A.
N.A.
0
13.3
0
P-Site Similarity:
100
100
100
40
N.A.
100
100
N.A.
100
33.3
13.3
20
N.A.
N.A.
6.6
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
21.2
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
41
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
46.6
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
80
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
8
0
0
8
8
0
8
0
0
0
0
0
8
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
22
8
0
15
0
0
0
22
0
8
% D
% Glu:
0
8
8
0
15
8
8
0
15
0
50
50
0
0
0
% E
% Phe:
0
0
8
0
0
0
15
0
0
8
0
0
8
8
0
% F
% Gly:
15
0
0
43
0
0
8
0
0
0
0
0
0
0
8
% G
% His:
0
43
0
0
0
0
0
0
0
0
0
0
8
0
0
% H
% Ile:
8
0
8
8
8
0
0
8
50
0
0
8
0
0
15
% I
% Lys:
50
22
0
15
0
8
0
8
0
0
8
15
0
8
0
% K
% Leu:
15
0
65
0
0
0
43
0
0
8
8
0
8
0
8
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
8
0
0
8
0
0
8
0
0
0
8
0
8
0
% N
% Pro:
0
0
0
8
0
0
0
8
0
0
15
8
0
8
8
% P
% Gln:
8
0
0
0
0
0
0
0
8
8
8
0
8
8
0
% Q
% Arg:
0
0
0
0
58
0
8
0
0
8
0
15
50
0
0
% R
% Ser:
0
8
8
8
8
0
0
58
0
15
8
0
0
43
0
% S
% Thr:
0
0
0
15
0
0
0
8
0
8
8
0
0
8
8
% T
% Val:
0
8
0
0
0
58
8
0
15
0
0
0
0
8
43
% V
% Trp:
0
0
0
8
0
0
8
0
0
43
0
0
0
0
0
% W
% Tyr:
0
0
8
0
0
0
0
0
0
8
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _